Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Hepatocyte, Lung, Liver, Epithelial Cell, Cell Culture
SUBMITTER: Axel Ducret
LAB HEAD: Axel Ducret
PROVIDER: PXD001988 | Pride | 2015-07-22
REPOSITORIES: Pride
Proteomics. Clinical applications 20150801 7-8
<h4>Purpose</h4>Cell surface proteins are the primary means for a cell to sense and interact with its environment and their dysregulation has been linked to numerous diseases. In particular, the identification of proteins specific to a single tissue type or to a given disease phenotype may enable the characterization of novel therapeutic targets. We tested here the feasibility of a cell surface proteomics approach to identify pertinent markers directly in a clinically relevant tissue.<h4>Experim ...[more]