Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Myometrial Cell, Myometrium
SUBMITTER: Craig Ulrich
LAB HEAD: Heather Burkin
PROVIDER: PXD002538 | Pride | 2019-04-10
REPOSITORIES: Pride
Copley Salem Christian C Ulrich Craig C Quilici David D Schlauch Karen K Buxton Iain L O ILO Burkin Heather H
Journal of biomechanics 20180330
Mechanical strain associated with the expanding uterus correlates with increased preterm birth rates. Mechanical signals result in a cascading network of protein phosphorylation events. These signals direct cellular activities and may lead to changes in contractile phenotype and calcium signaling. In this study, the complete phospho-proteome of uterine smooth muscle cells subjected to mechanical strain for 5 min was compared to un-strained controls. Statistically significant, differential phosph ...[more]