How C/EBPa creates an elite cell state for reprogramming to pluripotency

ABSTRACT: Mouse B cells, upon ectopic expression of the transcription factor C/EBPalpha for 18h, can be reprogrammed to induced pluripotent stem (iPS) cells with extremely high efficiency. To understand the molecular control of this phenomenon we performed a time course proteomic analysis by label-free protein quantification of proteins during B cell reprogramming to iPS cells.

OTHER RELATED OMICS DATASETS IN: PRJNA227547 PRJNA198734 PRJNA227776 PRJNA227774

INSTRUMENT(S):

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): B Cell, Embryonic Stem Cell

SUBMITTER: Michael Wierer  

LAB HEAD: Matthias Mann

PROVIDER: PXD002769 | Pride | 2016-02-24

REPOSITORIES: Pride