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Proteome-wide analysis of lysine succinylation in 5 organisms

ABSTRACT: Recent studies have revealed the physiological significance of post-translational lysine acylations in regulation of various cellular processes. Lysine succinylation is one of recently discovered post-translational acylations. To understand the distribution of lysine succinylations in five representative bacteria: Geobacillus kaustophilus, Thermus thermophilus, Escherichia coli, Bacillus subtilis, and Rhodothermus marinus.

INSTRUMENT(S): micrOTOF-Q II

ORGANISM(S): Thermus Thermophilus (strain Hb8 / Atcc 27634 / Dsm 579) Geobacillus Kaustophilus Hta426 Rhodothermus Marinus (strain Atcc 43812 / Dsm 4252 / R-10) (rhodothermus Obamensis) Escherichia Coli (strain K12 / W3110 / Atcc 27325 / Dsm 5911) Bacillus Subtilis Subsp. Subtilis Str. 168

SUBMITTER: Hiroki Okanishi

LAB HEAD: Ryoji Masui

PROVIDER: PXD002833 | Pride | 2016-12-14

REPOSITORIES: Pride

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Proteome-wide identification of lysine succinylation in thermophilic and mesophilic bacteria.

Okanishi Hiroki H Kim Kwang K Fukui Kenji K Yano Takato T Kuramitsu Seiki S Masui Ryoji R

Biochimica et biophysica acta. Proteins and proteomics 20161123 2

Lysine succinylation, one of post-translational acylations conserved from eukaryotes to bacteria, plays regulatory roles in various cellular processes. However, much remains unknown about the general and specific characteristics of lysine succinylation among bacteria, and about its functions different from those of other acylations. In this study, we characterized lysine succinylation, a newly discovered widespread type of lysine acylation in five bacterial species with different characteristics ...[more]

PMID: 27888076

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