Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap Velos
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Gut
SUBMITTER: Joshua Elias
LAB HEAD: Joshua E Elias
PROVIDER: PXD002838 | Pride | 2015-11-25
REPOSITORIES: Pride
Lichtman Joshua S JS Alsentzer Emily E Jaffe Mia M Sprockett Daniel D Masutani Evan E Ikwa Elvis E Fragiadakis Gabriela K GK Clifford David D Huang Bevan Emma BE Sonnenburg Justin L JL Huang Kerwyn Casey KC Elias Joshua E JE
The ISME journal 20151117 5
Endogenous intestinal microbiota have wide-ranging and largely uncharacterized effects on host physiology. Here, we used reverse-phase liquid chromatography-coupled tandem mass spectrometry to define the mouse intestinal proteome in the stomach, jejunum, ileum, cecum and proximal colon under three colonization states: germ-free (GF), monocolonized with Bacteroides thetaiotaomicron and conventionally raised (CR). Our analysis revealed distinct proteomic abundance profiles along the gastrointestin ...[more]