Cross-linking of mouse laminin 111

ABSTRACT: Laminin, a ~800 kD heterotrimeric protein, is a major functional component of the extracellular matrix, contributing to tissue development and maintenance. We used cross-linking and mass spectrometry to determine the order of subunits in the ~750 Å trimeric coiled-coil oligomerization domain of laminin and to achieve an estimate of the register of the three subunits along the length of the coiled coil.

INSTRUMENT(S):

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Cell Culture

SUBMITTER: Gad Armony  

LAB HEAD: Deborah Fass

PROVIDER: PXD004898 | Pride | 2016-12-22

REPOSITORIES: Pride