Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Carotid Artery
SUBMITTER: Xiaoke Yin
LAB HEAD: Manuel Mayr
PROVIDER: PXD005130 | Pride | 2017-04-20
REPOSITORIES: Pride
The Journal of clinical investigation 20170320 4
<h4>Background</h4>The identification of patients with high-risk atherosclerotic plaques prior to the manifestation of clinical events remains challenging. Recent findings question histology- and imaging-based definitions of the "vulnerable plaque," necessitating an improved approach for predicting onset of symptoms.<h4>Methods</h4>We performed a proteomics comparison of the vascular extracellular matrix and associated molecules in human carotid endarterectomy specimens from 6 symptomatic versus ...[more]