Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Fusion Lumos
ORGANISM(S): Homo Sapiens (human) Heterocephalus Glaber Cavia Porcellus (guinea Pig)
TISSUE(S): Liver
SUBMITTER: Joanna Kirkpatrick
LAB HEAD: Alessandro Ori
PROVIDER: PXD008720 | Pride | 2018-06-21
REPOSITORIES: Pride
BMC biology 20180802 1
<h4>Background</h4>Mammals display a wide range of variation in their lifespan. Investigating the molecular networks that distinguish long- from short-lived species has proven useful to identify determinants of longevity. Here, we compared the livers of young and old long-lived naked mole-rats (NMRs) and the phylogenetically closely related, shorter-lived, guinea pigs using an integrated omics approach.<h4>Results</h4>We found that NMR livers display a unique expression pattern of mitochondrial ...[more]