Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Liver
SUBMITTER: Ahmad Borzoo
LAB HEAD: Rovshan G. Sadygov
PROVIDER: PXD009493 | Pride | 2019-04-10
REPOSITORIES: Pride
Journal of proteome research 20210304 4
Metabolic labeling followed by LC-MS-based proteomics is a powerful tool to study proteome dynamics in high-throughput experiments both <i>in vivo</i> and <i>in vitro.</i> High mass resolution and accuracy allow differentiation in isotope profiles and the quantification of partially labeled peptide species. Metabolic labeling duration introduces a time domain in which the gradual incorporation of labeled isotopes is recorded. Different stable isotopes are used for labeling. Labeling with heavy w ...[more]