METTL13 modulates mRNA translation through methylation of eEF1A at Lys55 and the N-terminus
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ABSTRACT: The experiment aimed at identifying lysine methylation dependent interactions for eEF1A. FLAG-tagged wild type eEF1A and a methylation deficient mutant, carrying lysine-to-arginine mutations of the well-established methylation sites (Lys36, Lys55, Lys79, Lys165 and Lys318) were overexpressed in HEK-293 cells and co-purifying proteins were quantified using the MaxLFQ algorithm. FLAG-tagged
INSTRUMENT(S):
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Diploid Cell
DISEASE(S): Cervix Carcinoma
SUBMITTER:
Magnus Jakobsson
LAB HEAD: Jesper Velgard Olsen
PROVIDER: PXD009895 | Pride | 2018-07-04
REPOSITORIES: Pride
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