Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Homo Sapiens (human)
SUBMITTER: Oliver Schilling
LAB HEAD: Oliver Schilling
PROVIDER: PXD009905 | Pride | 2020-05-26
REPOSITORIES: Pride
Capponi Simona S Stöffler Nadja N Irimia Manuel M Van Schaik Frederik M A FMA Ondik Mercedes M MM Biniossek Martin L ML Lehmann Lisa L Mitschke Julia J Vermunt Marit W MW Creyghton Menno P MP Graybiel Ann M AM Reinheckel Thomas T Schilling Oliver O Blencowe Benjamin J BJ Crittenden Jill R JR Timmers H Th Marc HTM
RNA biology 20190927 1
Neuronal microexons represent the most highly conserved class of alternative splicing events and their timed expression shapes neuronal biology, including neuronal commitment and differentiation. The six-nt microexon 34' is included in the neuronal form of <i>TAF1</i> mRNA, which encodes the largest subunit of the basal transcription factor TFIID. In this study, we investigate the tissue distribution of <i>TAF1-34'</i> mRNA and protein and the mechanism responsible for its neuronal-specific spli ...[more]