Dataset Information

Transmission of Cricket paralysis virus via exosome-like vesicles during infection of Drosophila cells

ABSTRACT: Examining the role of exosomes in the life cycle of CrPV in Drosophila Melanogaster. sing prquantitative proteomics we find CrPV proteins in exosome-like vesicles, which upon further aanalysis appear to facilitate infection.

INSTRUMENT(S):

ORGANISM(S): Drosophila Melanogaster (fruit Fly)

TISSUE(S): Cell Culture

SUBMITTER: Craig Kerr

LAB HEAD: Leonard J. Foster

PROVIDER: PXD011271 | Pride | 2018-11-14

REPOSITORIES: Pride

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Dataset's files

Source:

			Action	DRS
	Cell_Pellet_6hpi_Results.zip	Other
	CrPV_ProteinDB-Only_04232014.fasta	Fasta
	D_melanogaster_DB_04232014.fasta	Fasta
	Exosomes_CrPV6hpi_Results.zip	Other
	S2CellPellet_6hpi_rep1_20150417.raw	Raw

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Publications

Transmission of Cricket paralysis virus via exosome-like vesicles during infection of Drosophila cells.

Kerr Craig H CH Dalwadi Udit U Scott Nichollas E NE Yip Calvin K CK Foster Leonard J LJ Jan Eric E

Scientific reports 20181126 1

Viruses are classically characterized as being either enveloped or nonenveloped depending on the presence or absence of a lipid bi-layer surrounding their proteinaceous capsid. In recent years, many studies have challenged this view by demonstrating that some nonenveloped viruses (e.g. hepatitis A virus) can acquire an envelope during infection by hijacking host cellular pathways. In this study, we examined the role of exosome-like vesicles (ELVs) during infection of Drosophilia melanogaster S2 ...[more]

PMID: 30478341

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