Proteomics

Dataset Information

2

Saliva proteomic patterns in patients with and without molar incisor hypomineralization Proteins exclusively detected in MIH saliva in molar incisor hypomineralization: a proteomic profiling


ABSTRACT: Molar incisor hypomineralization (MIH) is an endemic pediatric disease with an unclear pathogenesis. Considering that saliva control remineralization of enamel and that MIH is associated with higher saliva flow rate it is reasonable to suggest that also the composition of saliva is affected by the disease.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Homo sapiens  

TISSUE(S): Saliva

DISEASE(S): Amelogenesis Imperfecta Type 3a

SUBMITTER: Goran Mitulović  

LAB HEAD: Goran Mitulović

PROVIDER: PXD016126 | Pride | 2020-05-12

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
MIH_K1.raw Raw
MIH_K2.raw Raw
MIH_K3.raw Raw
MIH_K4.raw Raw
MIH_K5.raw Raw
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Publications

Saliva proteomic patterns in patients with molar incisor hypomineralization.

Bekes K K   Mitulović G G   Meißner N N   Resch U U   Gruber R R  

Scientific reports 20200505 1


Molar incisor hypomineralization (MIH) is an endemic pediatric disease with an unclear pathogenesis. Considering that saliva controls enamel remineralization and that MIH is associated with higher saliva flow rate, we hypothesized that the protein composition of saliva is linked to disease. To test this, we enrolled 5 children aged 6-14 years with MIH showing at least one hypersensitive molar and 5 caries-free children without hypomineralization. Saliva samples were subjected to proteomic analys  ...[more]

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