Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Fusion Lumos, impact II
ORGANISM(S): Bos Taurus (bovine) Escherichia Coli
SUBMITTER: Julian Langer
LAB HEAD: Julian Langer
PROVIDER: PXD021574 | Pride | 2020-11-09
REPOSITORIES: Pride
Nature communications 20201104 1
Understanding the conformational sampling of translation-arrested ribosome nascent chain complexes is key to understand co-translational folding. Up to now, coupling of cysteine oxidation, disulfide bond formation and structure formation in nascent chains has remained elusive. Here, we investigate the eye-lens protein γB-crystallin in the ribosomal exit tunnel. Using mass spectrometry, theoretical simulations, dynamic nuclear polarization-enhanced solid-state nuclear magnetic resonance and cryo- ...[more]