Proteomics

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Dire wolves were the last of an ancient New World canid lineage

ABSTRACT: Phylogenetic analysis of the extinct dire wolf was carried out to explore the relationship this species had with other Canids.

INSTRUMENT(S): Q Exactive HF

ORGANISM(S): Canis Dirus

TISSUE(S): Bone Marrow

SUBMITTER: Samantha Presslee  

LAB HEAD: Prof. Oliver Craig

PROVIDER: PXD021930 | Pride | 2020-11-02

REPOSITORIES: Pride

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Dire wolves were the last of an ancient New World canid lineage.

Perri Angela R AR   Mitchell Kieren J KJ   Mouton Alice A   Álvarez-Carretero Sandra S   Hulme-Beaman Ardern A   Haile James J   Jamieson Alexandra A   Meachen Julie J   Lin Audrey T AT   Schubert Blaine W BW   Ameen Carly C   Antipina Ekaterina E EE   Bover Pere P   Brace Selina S   Carmagnini Alberto A   Carøe Christian C   Samaniego Castruita Jose A JA   Chatters James C JC   Dobney Keith K   Dos Reis Mario M   Evin Allowen A   Gaubert Philippe P   Gopalakrishnan Shyam S   Gower Graham G   Heiniger Holly H   Helgen Kristofer M KM   Kapp Josh J   Kosintsev Pavel A PA   Linderholm Anna A   Ozga Andrew T AT   Presslee Samantha S   Salis Alexander T AT   Saremi Nedda F NF   Shew Colin C   Skerry Katherine K   Taranenko Dmitry E DE   Thompson Mary M   Sablin Mikhail V MV   Kuzmin Yaroslav V YV   Collins Matthew J MJ   Sinding Mikkel-Holger S MS   Gilbert M Thomas P MTP   Stone Anne C AC   Shapiro Beth B   Van Valkenburgh Blaire B   Wayne Robert K RK   Larson Greger G   Cooper Alan A   Frantz Laurent A F LAF  

Nature 20210113 7848

Dire wolves are considered to be one of the most common and widespread large carnivores in Pleistocene America<sup>1</sup>, yet relatively little is known about their evolution or extinction. Here, to reconstruct the evolutionary history of dire wolves, we sequenced five genomes from sub-fossil remains dating from 13,000 to more than 50,000 years ago. Our results indicate that although they were similar morphologically to the extant grey wolf, dire wolves were a highly divergent lineage that spl  ...[more]

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