Ontology highlight
ABSTRACT:
INSTRUMENT(S): timsTOF Pro
ORGANISM(S): Homo Sapiens (human)
SUBMITTER: Pietro Scaturro
LAB HEAD: Pietro Scaturro
PROVIDER: PXD022789 | Pride | 2022-04-02
REPOSITORIES: Pride
Wanner Nicola N Andrieux Geoffroy G Badia-I-Mompel Pau P Edler Carolin C Pfefferle Susanne S Lindenmeyer Maja T MT Schmidt-Lauber Christian C Czogalla Jan J Wong Milagros N MN Okabayashi Yusuke Y Braun Fabian F Lütgehetmann Marc M Meister Elisabeth E Lu Shun S Noriega Maria L M MLM Günther Thomas T Grundhoff Adam A Fischer Nicole N Bräuninger Hanna H Lindner Diana D Westermann Dirk D Haas Fabian F Roedl Kevin K Kluge Stefan S Addo Marylyn M MM Huber Samuel S Lohse Ansgar W AW Reiser Jochen J Ondruschka Benjamin B Sperhake Jan P JP Saez-Rodriguez Julio J Boerries Melanie M Hayek Salim S SS Aepfelbacher Martin M Scaturro Pietro P Puelles Victor G VG Huber Tobias B TB
Nature metabolism 20220328 3
Extrapulmonary manifestations of COVID-19 have gained attention due to their links to clinical outcomes and their potential long-term sequelae<sup>1</sup>. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) displays tropism towards several organs, including the heart and kidney. Whether it also directly affects the liver has been debated<sup>2,3</sup>. Here we provide clinical, histopathological, molecular and bioinformatic evidence for the hepatic tropism of SARS-CoV-2. We find that l ...[more]