Dataset Information


Pathological Features of Enterovirus 71-associated Brain and Lung Damage in Mice Based on Quantitative Proteomic Analyses

ABSTRACT: Enterovirus 71 (EV71), a member of the Enterovirus genus in the Picornaviridae family, was first recognized as a dermotrophic virus that usually cause mild, self-limiting hand-foot-and-mouth disease (HFMD). However, EV71 infection can sometimes induce a variety of severe neurological complications, pulmonary edema and even death. Here, we aimed to provide an overview of proteomics characterization of EV71-infected brain and lung tissues.

INSTRUMENT(S): Q Exactive Plus

ORGANISM(S): Mus musculus  

TISSUE(S): Brain, Lung

DISEASE(S): Not Available

SUBMITTER: Yuefei Jin  

LAB HEAD: Yuefei Jin

PROVIDER: PXD023819 | Pride | 2021-09-10


Dataset's files

Action DRS
Z8314TQ_1.raw Raw
Z8314TQ_10.raw Raw
Z8314TQ_11.raw Raw
Z8314TQ_12.raw Raw
Z8314TQ_13.raw Raw
Items per page:
1 - 5 of 41
altmetric image


Pathological Features of Enterovirus 71-Associated Brain and Lung Damage in Mice Based on Quantitative Proteomic Analysis.

Jin Yuefei Y   Li Dong D   Sun Tiantian T   Du Yue Y   Gao Yanlei Y   Ding Ronghua R   Ji Wangquan W   Zhang Weiguo W   Yang Haiyan H   Chen Shuaiyin S   Duan Guangcai G  

Frontiers in microbiology 20210618

The outbreaks of enterovirus 71 (EV71)-associated hand, foot, and mouth disease (HFMD) have emerged as an emergency of global health due to its association with fatal encephalitis and subsequent neurogenic pulmonary edema; however, the molecular characteristics and pathological features underlying EV71-associated encephalitis and pulmonary edema remain largely unknown. In this study, we performed a proteomic analysis of fresh brain and lung tissues from EV71-infected mice at 7 days post infectio  ...[more]

Similar Datasets

2022-01-24 | PXD030940 | Pride
2021-06-14 | PXD014915 | Pride
2021-05-30 | PXD025997 | Pride
2020-12-14 | PXD019035 | Pride
2021-09-09 | PXD023080 | Pride
2021-05-17 | PXD023311 | Pride
2020-10-19 | PXD016199 | Pride
2020-12-02 | PXD019033 | Pride
2019-11-12 | PXD008176 | Pride
2021-04-06 | PXD017616 | Pride