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Discovery of biomarkers with clinical utility for recurrent aphthous stomatitis using saliva as liquid biopsy and mass spectrometry-based proteomics

ABSTRACT: The objective of this project was to characterize the salivary proteome of patients with recurrent aphthous stomatitis using mass spectrometry-based proteomics(nLC-MS/MS) and assess its clinical usefulness in identifying the most representative biological and molecular processes during the course of lesions. To do this, we conducted a case-control study, analyzing the saliva of healthy controls and patients with recurrent aphthous stomatitis during a complete ulcerative cycle (active ulcers and absence of lesions).

INSTRUMENT(S): timsTOF Pro

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Saliva

DISEASE(S): Aphthous Stomatitis

SUBMITTER: César Rivera

LAB HEAD: César Rivera

PROVIDER: PXD026401 | Pride | 2021-06-17

REPOSITORIES: Pride

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