Viral fallout: Semen proteome reveals COVID-19 dysregulates several biological processes linked to male reproductive function

ABSTRACT: The current global outbreak of COVID-19 has significantly impacted several organ systems. Male reproductive organs are among the potential targets of SARS-CoV-2 infection owing to the presence of abundant viral receptors; ACE2 and TMPRSS2 in the testis. However, the questions pertaining to the long term effects of SARS-CoV-2 infection on male fertility are still unanswered. For this study, we procured the semen samples of COVID-19 recovered patients and performed mass spectrometry based proteomic studies to understand the impact of the disease on the biological processes involved in reproductive health.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Semen, Sperm

DISEASE(S): Covid-19

SUBMITTER: Avinash singh  

LAB HEAD: Sanjeeva Srivastava

PROVIDER: PXD026703 | Pride | 2022-04-04

REPOSITORIES: Pride