Proteomics

Dataset Information

0

LC-MS/MS of differentiated bone marrow and Yolk sac macrophages


ABSTRACT: We immortalized hematopoietic progenitors from Yolk sac (YS) and bone marrow (BM) using conditional homeobox protein Hox-B8 (Hoxb8) and carried out global protein profiling using a bottom-up approach.

INSTRUMENT(S):

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Early Embryonic Cell, Macrophage

DISEASE(S): Disease Free

SUBMITTER: Elke Hammer  

LAB HEAD: Elke Hammer

PROVIDER: PXD026916 | Pride | 2025-08-07

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
190226_OV4_UL_DZHKe_BM_J1.raw Raw
190226_OV4_UL_DZHKe_BM_J2.raw Raw
190226_OV4_UL_DZHKe_BM_J3.raw Raw
190226_OV4_UL_DZHKe_YS_J1.raw Raw
190226_OV4_UL_DZHKe_YS_J2.raw Raw
Items per page:
1 - 5 of 10
altmetric image

Publications


<h4>Background</h4>Tissue-resident macrophages have mixed developmental origins. They derive in variable extent from yolk sac (YS) hematopoiesis during embryonic development. Bone marrow (BM) hematopoietic progenitors give rise to tissue macrophages in postnatal life, and their contribution increases upon organ injury. Since the phenotype and functions of macrophages are modulated by the tissue of residence, the impact of their origin and developmental paths has remained incompletely understood.  ...[more]

Similar Datasets

2022-02-04 | PXD026922 | Pride
2011-09-01 | GSE30244 | GEO
2011-08-31 | E-GEOD-30244 | biostudies-arrayexpress
2023-03-01 | E-MTAB-10552 | biostudies-arrayexpress
2023-03-01 | E-MTAB-10888 | biostudies-arrayexpress
2022-12-07 | E-MTAB-11673 | biostudies-arrayexpress
2025-01-01 | GSE241060 | GEO
2015-12-31 | E-GEOD-69204 | biostudies-arrayexpress
| PRJEB51812 | ENA
2015-12-31 | GSE69204 | GEO