Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Homo Sapiens (human)
SUBMITTER: Sindhuja Sridharan
LAB HEAD: Mikhail M. Savitski
PROVIDER: PXD027769 | Pride | 2022-08-09
REPOSITORIES: Pride
Items per page: 1 - 5 of 199 |
Nature chemical biology 20220721 10
Reversible protein phosphorylation is an important mechanism for regulating (dis)assembly of biomolecular condensates. However, condensate-specific phosphosites remain largely unknown, thereby limiting our understanding of the underlying mechanisms. Here, we combine solubility proteome profiling with phosphoproteomics to quantitatively map several hundred phosphosites enriched in either soluble or condensate-bound protein subpopulations, including a subset of phosphosites modulating protein-RNA ...[more]