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Histone post-translational modification analysis of Aspergillus strains

ABSTRACT: Chemical modifications of DNA and histone proteins impact the organization of chromatin within the nucleus. Changes in these modifications, catalyzed by different chromatin-modifying enzymes, influence chromatin organization, which in turn is thought to impact the spatial and temporal regulation of gene expression. While combinations of different histone modifications, the histone code, have been studied in several model species, we know very little about histone modifications in the fungal genus Aspergillus, whose members are generally well-studied due to their importance as models in cell and molecular biology as well as their medical and biotechnological relevance.

INSTRUMENT(S): Q Exactive Plus, Q Exactive HF

ORGANISM(S): Neosartorya Fumigata (aspergillus Fumigatus) Aspergillus Niger Emericella Nidulans (aspergillus Nidulans)

SUBMITTER: Roberta Noberini

LAB HEAD: Tiziana Bonaldi

PROVIDER: PXD033478 | Pride | 2022-06-30

REPOSITORIES: Pride

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The histone code of the fungal genus <i>Aspergillus</i> uncovered by evolutionary and proteomic analyses.

Zhang Xin X Noberini Roberta R Bonaldi Tiziana T Collemare Jerome J Seidl Michael F MF

Microbial genomics 20220901 9

Chemical modifications of DNA and histone proteins impact the organization of chromatin within the nucleus. Changes in these modifications, catalysed by different chromatin-modifying enzymes, influence chromatin organization, which in turn is thought to impact the spatial and temporal regulation of gene expression. While combinations of different histone modifications, the histone code, have been studied in several model species, we know very little about histone modifications in the fungal genu ...[more]

PMID: 36129736

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