Bifidobacterium infantis utilizes N-acetylglucosamine nitrogen
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ABSTRACT: 15N-labeled N-acetylglucosamine (NAG) fed to B. infantis cells are incorporated into its proteome. This indicates that NAG, an amino sugar residue of human milk oligosaccharides (HMO) and other biopolymers, is used as a nitrogen source. Transcriptomics while subsisting on NAG nitrogen are consistent with the proteomics results. This further indicates that B. infantis utilizes NAG nitrogen in and shunts it towards a fundamental cellular processes.
INSTRUMENT(S): Orbitrap Fusion
ORGANISM(S): Bifidobacterium Longum Subsp. Infantis (strain Atcc 15697 / Dsm 20088 / Jcm 1222 / Nctc 11817 / S12) Bacteria
TISSUE(S): Primary Cell Line Cell
SUBMITTER: Asha Rani
LAB HEAD: David A. Sela
PROVIDER: PXD035809 | Pride | 2023-05-18
REPOSITORIES: Pride
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