Proteomics

Dataset Information

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Bifidobacterium infantis utilizes N-acetylglucosamine nitrogen


ABSTRACT: 15N-labeled N-acetylglucosamine (NAG) fed to B. infantis cells are incorporated into its proteome. This indicates that NAG, an amino sugar residue of human milk oligosaccharides (HMO) and other biopolymers, is used as a nitrogen source. Transcriptomics while subsisting on NAG nitrogen are consistent with the proteomics results. This further indicates that B. infantis utilizes NAG nitrogen in and shunts it towards a fundamental cellular processes.

INSTRUMENT(S): Orbitrap Fusion

ORGANISM(S): Bifidobacterium Longum Subsp. Infantis (strain Atcc 15697 / Dsm 20088 / Jcm 1222 / Nctc 11817 / S12) Bacteria

TISSUE(S): Primary Cell Line Cell

SUBMITTER: Asha Rani  

LAB HEAD: David A. Sela

PROVIDER: PXD035809 | Pride | 2023-05-18

REPOSITORIES: Pride

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