Identification of cell surface proteins in Zdhhc20 KO cells
Ontology highlight
ABSTRACT: An shRNA screen to search for the mediators of pancreatic cancer metastasis identified palmitoyl transferase ZDHHC20 as a protein that mediates this process by promoting the outgrowth of metastatic cells in vivo, We generated a KO of Zdhhc20 using Cas9/CRISPR and sought to determine the changes in the cell surface proteome in KO cells versus parental cells.
INSTRUMENT(S): Orbitrap Fusion Lumos
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Cell Culture, Pancreatic Duct
DISEASE(S): Pancreatic Cancer
SUBMITTER:
Goran Tomic
LAB HEAD: Julian Downward
PROVIDER: PXD038384 | Pride | 2023-02-09
REPOSITORIES: Pride
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