Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive HF
ORGANISM(S): Ixodes Scapularis (black-legged Tick) (deer Tick) Oryctolagus Cuniculus (rabbit)
SUBMITTER: Albert Mulenga
LAB HEAD: Albert Mulenga
PROVIDER: PXD038685 | Pride | 2023-03-11
REPOSITORIES: Pride
Mulenga Albert A Radulovic Zeljko Z Porter Lindsay L Britten Taylor Hollman TH Kim Tae Kwon TK Tirloni Lucas L Gaithuma Alex Kiarie AK Adeniyi-Ipadeola Grace O GO Dietrich Jolene K JK Moresco James J JJ Yates John R JR
Scientific reports 20221209 1
Ixodes scapularis long-term blood feeding behavior is facilitated by a tick secreted bio adhesive (tick cement) that attaches tick mouthparts to skin tissue and prevents the host from dislodging the attached tick. Understanding tick cement formation is highly sought after as its disruption will prevent tick feeding. This study describes proteins that form the inner core layer of I. scapularis tick cement as disrupting these proteins will likely stop formation of the outer cortical layer. The inn ...[more]