Ontology highlight
ABSTRACT:
INSTRUMENT(S): Bruker Daltonics timsTOF series
ORGANISM(S): Homo Sapiens (human) Human Immunodeficiency Virus 1
SUBMITTER: Joerg Doellinger
LAB HEAD: Peter Lasch
PROVIDER: PXD046777 | Pride | 2024-01-26
REPOSITORIES: Pride
Köppke Julia J Keller Luise-Elektra LE Stuck Michelle M Arnow Nicolas D ND Bannert Norbert N Doellinger Joerg J Cingöz Oya O
Nature communications 20240105 1
Viruses that carry a positive-sense, single-stranded (+ssRNA) RNA translate their genomes soon after entering the host cell to produce viral proteins, with the exception of retroviruses. A distinguishing feature of retroviruses is reverse transcription, where the +ssRNA genome serves as a template to synthesize a double-stranded DNA copy that subsequently integrates into the host genome. As retroviral RNAs are produced by the host cell transcriptional machinery and are largely indistinguishable ...[more]