Dataset Information

Proteomic analyses reveal the key role of gene co-option in the evolution of Scaly-foot Snail scleritome

ABSTRACT: This project aims to uncover the co-option and preservation of ancient proteins through the process of sclerite development in deep-sea creature Chrysomallon Squamiferum. Proteomes of the evolutionarily novel hard part, the sclerite and the long conserved spirial shell were studied, in comparison to the shell proteome of the confimilial species Gigantopelta aegis, which resides the same habitate. Proteins were extracted from the biomineralized hard parts and we employed LC-MS/MS to identify the proteins contained in those hard parts. Transcriptomic analysis was accompanied to undergo a more throughout study.

INSTRUMENT(S): Orbitrap Fusion Lumos

ORGANISM(S): Gigantopelta Aegis Chrysomallon Squamiferum

TISSUE(S): Exoskeleton

SUBMITTER: Wai Chuen WONG

LAB HEAD: Pei-Yuan QIAN

PROVIDER: PXD051659 | Pride | 2025-05-06

REPOSITORIES: Pride

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Proteomic analyses reveal the key role of gene co-option in the evolution of the scaly-foot snail scleritome.

Wong Wai Chuen WC Kwan Yick Hang YH He Xing X Chen Chong C Xiang Shengling S Xiao Yao Y Long Lexin L Gao Kexin K Wang Ning N Wu Longjun L Qian Pei-Yuan PY Sun Jin J

Communications biology 20250228 1

Biomineralization, a key driving force underlying dramatic morphological diversity, is widely adopted by metazoans to incorporate inorganic minerals into their organic matrices. The scaly-foot snail Chrysomallon squamiferum from deep-sea hot vents uniquely possesses hundreds of sclerites on its foot in addition to a coiled shell, providing an exclusive case to study the formation of evolutionarily novel hard parts. Here, we identified the matrix proteins present in the exoskeletons of C. squamif ...[more]

PMID: 40021717

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			Action	DRS
	Gae_searchdatabase.fasta	Fasta
	Orbitrap_PDresults.zip	Other
	Orbitrap_mgf.zip	Other
	Orbitrap_raw.zip	Other
	SFG_searchdatabase.fasta	Fasta