LC-MSMS in axenically cultured C. elegans
Ontology highlight
ABSTRACT:
INSTRUMENT(S):
ORGANISM(S): Caenorhabditis Elegans
TISSUE(S): Whole Body
SUBMITTER: 
Ping Wu
LAB HEAD: Bart P.Braeckman
PROVIDER: PXD053074 | Pride | 2025-07-21
REPOSITORIES: Pride
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| EV_ADR_R1_analysis.tdf | Other | |||
| EV_ADR_R1_analysis.tdf_bin | Other | |||
| EV_ADR_R1_chromatography-data.sqlite | Sqlite | |||
| EV_ADR_R2_analysis.tdf | Other | |||
| EV_ADR_R2_analysis.tdf_bin | Other |
Items per page: 5 1 - 5 of 62 |
Publications
The Proprotein Convertase BLI-4 Is Required for Axenic Dietary Restriction Mediated Longevity in Caenorhabditis elegans.
Wu Ping P Vandemeulebroucke Lieselot L Cai Huaihan H Braeckman Bart P BP
Aging cell 20250408 7
Dietary restriction (DR) is a well-established method for extending lifespan across various species, including C. elegans. Among the different DR regimens, axenic dietary restriction (ADR), in which worms are grown in a nutrient-rich sterile liquid medium, yields the most powerful lifespan extension. However, the molecular mechanisms underlying this longevity phenotype remain largely unexplored. Through a pilot screen of candidate genes, we identified the proprotein convertase BLI-4 as a crucial ...[more]
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