Proteomics

Dataset Information

Unravelling the Proteomic Landscape of Imipenem Resistance in Pseudomonas aeruginosa: A Comparative Investigation between Clinical and Control Strains

ABSTRACT: The proteomic landscape of Pseudomonas aeruginosa under the influence of Imipenem, a commonly used antibiotic, has been the subject of investigation in this study. Our comparative analysis between the world epidemic clinical strain (6378/09) and the control strain (ATCC 27853)has revealed results highlighting the proteomic changes that occur in response to varying Imipenem concentrations. Utilizing label-free quantification (LFQ) intensity scores, protein-level t-tests, and Gene Ontology (GO) enrichment analysis, we have been able to delve deeper into the molecular mechanisms that underpin Imipenem resistance.

INSTRUMENT(S):

ORGANISM(S): Pseudomonas Aeruginosa Atcc 700888

SUBMITTER: Animesh Sharma  

LAB HEAD: Francesca Di Bartolomeo

PROVIDER: PXD055744 | Pride | 2026-04-13

REPOSITORIES: Pride

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