Ethanol Exposure during Differentiation of Human Induced Pluripotent Stem Cells Reduces Cardiomyocyte Generation and Alters Metabolism

ABSTRACT: In this study, we investigated the effects of ethanol exposure on cardiomyocyte differentiation by treating the cells with various concentrations of ethanol. The results indicated that ethanol exposure during hiPSC-CM differentiation reduced cell viability, cell proliferation, and cardiomyocyte yield, and caused mitochondrial dysfunction, redox imbalance, and changes of proteomic profiles.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

SUBMITTER: Longping Fu  

LAB HEAD: Ronghu Wu

PROVIDER: PXD056092 | Pride | 2025-05-23

REPOSITORIES: Pride