Pulldown of Maspin-GST in Human Cells Treated or Untreated with Nocodazole
Ontology highlight
ABSTRACT:
INSTRUMENT(S):
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Epithelial Cell
DISEASE(S): Breast Cancer
SUBMITTER: 
Julia Cunha
LAB HEAD: Julia P.C da Cunha, Nathalie Cella
PROVIDER: PXD057847 | Pride | 2025-09-01
REPOSITORIES: Pride
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| JC_1A_230603112636.raw | Raw | |||
| JC_1B_230603131333.raw | Raw | |||
| JC_1C_230603150033.raw | Raw | |||
| JC_1D.raw | Raw | |||
| JC_2A_230603183457.raw | Raw |
Items per page: 5 1 - 5 of 10 |
Publications
Maspin/SerpinB5 is a cytoskeleton-binding protein that regulates epithelial cell shape.
da Silva Luiz E LE Paim Lia M G LMG Lyalina Tatiana T Menezes Ana P J APJ da Cunha Julia P C JPC Bechstedt Susanne S Cella Nathalie N
Communications biology 20250822 1
Maspin/SerpinB5 is an abundant and pleiotropic protein mostly expressed by epithelia. Initially described as a tumor suppressor, it has been reported as a regulator of cell adhesion, migration, and invasion. How intracellular Maspin orchestrates these processes is poorly understood. In this study, we utilized Affinity purification-Mass spectrometry (AP/MS) alongside in vitro reconstitution assays to establish that Maspin directly interacts with microtubules and microfilaments. Additionally, CRIS ...[more]
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