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Gastric ulcer mice gastric tissue

ABSTRACT: Indomethacin was applied to establish a mice model of gastric ulcer, 24 h later, gastric tissue were obtain

INSTRUMENT(S): timsTOF Pro

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Epithelial Cell, Gastric Mucosa

DISEASE(S): Gastric Ulcer

SUBMITTER: Yujun Hou

LAB HEAD: Yujun Hou

PROVIDER: PXD058482 | Pride | 2025-05-07

REPOSITORIES: pride

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			Action	DRS
	1_MWY-23-2498-b_DIA_mouse_933a_Slot2-13_1_8457.d.zip	Other
	1_MWY-23-2498-b_DIA_mouse_934a_Slot2-14_1_8458.d.zip	Other
	1_MWY-23-2498-b_DIA_mouse_935a_Slot2-15_1_8459.d.zip	Other
	1_MWY-23-2498-b_DIA_mouse_936a_Slot2-16_1_8460.d.zip	Other
	1_MWY-23-2498-b_DIA_mouse_937a_Slot2-17_1_8461.d.zip	Other

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Publications

The crucial role of neutrophil extracellular traps and IL-17 signaling in indomethacin-induced gastric injury in mice.

Hou Yujun Y Wang Wen W Ye Jiangnan J Sun Luqiang L Zhou Siyuan S Zheng Qianhua Q Shi Yunzhou Y Chen Ying Y Yao Junpeng J Wang Lu L Yan Xiangyun X Wan Renhong R Chen Shuai S Li Ying Y

Scientific reports 20250409 1

The homeostasis of gastric mucosa is extremely delicate. Neutrophils, the most abundant immune cells in human circulation, are regarded crutial in the regulation of gastric mucosal immune response. Non-steroidal anti-inflammatory drugs (NSAIDs) induced gastric injury is the second major reason for gastric ulcers. The relations between neutrophils and Indomethacin-induced gastric injury are not fully understood. A mouse model of gastric injury was established using Indomethacin, followed by prote ...[more]

PMID: 40204883

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