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Integrated omics approaches to explore a new system of genetic control of dibenzothiophene desulfurization in Gordonia alkanivorans strain 135 -- MS1

ABSTRACT: This project aims to explore a new system for genetic control of dibenzothiophene desulfurization in Gordonia alkanivorans strain 135 using integrated omics approaches. A quantitative protomics, RNA-Seq analysis was performed. RNA-seq results were further validated using qRT-PCR for differentially expressed genes.

INSTRUMENT(S):

ORGANISM(S): Gordonia Alkanivorans

TISSUE(S): Cell Culture

SUBMITTER: Tomiris Kusainova

LAB HEAD: Dr Irina A. Tarasova

PROVIDER: PXD058641 | Pride | 2025-05-07

REPOSITORIES: Pride

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			Action	DRS
	032024_DBT1.raw	Raw
	032024_DBT2.raw	Raw
	032024_DBT3.raw	Raw
	032024_DBT4.raw	Raw
	032024_DBT5.raw	Raw

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Publications

Integrated Omics Approaches to Explore a New System of Genetic Control of Dibenzothiophene Desulfurization and Aromatic Ring Cleavage by Gordonia alkanivorans Strain 135.

Frantsuzova Ekaterina E Bogun Alexander A Vetrova Anna A Kazakova Elizaveta E Kusainova Tomiris T Tarasova Irina I Pozdnyakova-Filatova Irina I Delegan Yanina Y

Biology 20250212 2

Dibenzothiophene (DBT) is a widespread environmental pollutant. The most common metabolic pathway for DBT degradation by Gordonia strains is the 4S pathway, which is under the control of the dsz operon. The ability to utilize DBT as the sole source of sulfur in Gordonia alkanivorans strain 135 has been revealed. The dsz operon was not detected in the genome of strain 135. In this work, using genomic, transcriptomic, and proteomic data of strain 135, it was shown that ...[more]

PMID: 40001956

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