Human endosomal proximity proteome

ABSTRACT: Here, using comparative proximity proteomics of critical retrieval sub-domain components Retromer and Retriever, their cargo adaptors, and a component of the opposing ESCRT-degradative sub-domain, we provide a data-rich resource that identifies new molecular details of retrieval sub-domain composition and organization, including an unrecognised complexity in the interface of Retromer with RAB GTPases.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Hela Cell

SUBMITTER: Carlos Anton-Plagaro  

LAB HEAD: Peter J. Cullen

PROVIDER: PXD061918 | Pride | 2025-08-04

REPOSITORIES: Pride