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ABSTRACT: This study examines how aging influences the proteomic landscape of human spermatozoa. Proteomic analysis was done on sperm samples from three groups of normal, fertile men: young adults (21–30 years), late adults (31–40 years), and advanced age (41–51 years). The analysis revealed dynamic age-related alterations in human sperm proteins potentially impacting key sperm physiological functions such as motility, metabolism, and fertilization.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Testis, Sperm

DISEASE(S): Infertility

SUBMITTER: Ayodele Alaiya  

LAB HEAD: Dr. Ayodele Alaiya

PROVIDER: PXD062650 | Pride | 2025-07-21

REPOSITORIES: Pride