Proteomic analysis of Cerebral organoid-derived exsome
Ontology highlight
ABSTRACT:
INSTRUMENT(S):
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Brain
SUBMITTER: 
Young Eun Kim
LAB HEAD: Dukjin Kang
PROVIDER: PXD063105 | Pride | 2026-04-27
REPOSITORIES: Pride
Dataset's files
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Publications
Comparative Multiomics Analysis of Cerebral Organoid-Derived Exosomes during Organoid Maturation.
Kim Young Eun YE Kim Seong Soon SS Lee Jangjae J Park Sung Bum SB Jo Jeong Hyeon JH Cho Hye Jin HJ Choi Kyoung Jin KJ Im Jeonghui J Seo Woo Rin WR Park Yeonji Y Kim Sunghwan S Bae Myung-Ae MA Kim Ki Young KY Cho Sung-Hee SH Kang Dukjin D Koh Byumseok B
Nano letters 20260331 14
Cerebral organoids derived from human pluripotent stem cells recapitulate key features of early brain development and provide a physiologically relevant model for neurogenesis. Exosomes secreted by these organoids carry bioactive cargo and offer a noninvasive means to monitor maturation and intercellular communication. We performed comprehensive multiomics profiling of exosomes collected from cerebral organoids at defined developmental stages to evaluate their utility as biomarkers of neuronal d ...[more]
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