Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Madurella Mycetomatis
TISSUE(S): Cell Culture
SUBMITTER: cathal murphy
LAB HEAD: Sean Doyle
PROVIDER: PXD063449 | Pride | 2025-05-15
REPOSITORIES: Pride
Action | DRS | |||
---|---|---|---|---|
Iron_deplete_MM_A.msf | Msf | |||
Iron_deplete_MM_A.raw | Raw | |||
Iron_deplete_MM_B.msf | Msf | |||
Iron_deplete_MM_B.raw | Raw | |||
Iron_deplete_MM_C.msf | Msf |
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Nature communications 20250625 1
Mycetoma is a chronic granulomatous infection of the subcutaneous tissue, most often caused by the fungal pathogen Madurella mycetomatis. Characteristic of the infection is the formation of grains. However, knowledge of the function and formation of the grain is limited. Here, we use a Galleria mellonella larvae infection model and transcriptomic profiling to identify processes associated with M. mycetomatis grain formation. Larvae were infected with M. mycetomatis and, after 4, 24, 72 and 168 h ...[more]