Dataset Information

Extracellular vesicles in Early preterm neonates and thrombin generation

ABSTRACT: The aim of the EVENT Study (Extracellular Vesicles in Early preterm Neonates and Thrombin generation) was to characterise the circulating EVs in preterm infants, using multiple EV charac- terisation techniques, during the perinatal adaptation period and compare them to healthy full-term controls.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Platelet, Blood Plasma

DISEASE(S): Low Birth Weight

SUBMITTER: Daniel O Reilly

LAB HEAD: Patricia Maguire

PROVIDER: PXD064962 | Pride | 2026-01-11

REPOSITORIES: Pride

ACCESS DATA

Dataset's files

Source:

			Action	DRS
	2022_09_20_LWEISS_EVENT_PT_D1_16_1_S1-A1_6641.d.zip	Other
	2022_09_20_LWEISS_EVENT_PT_D1_16_2_S1-B1_6642.d.zip	Other
	2022_09_20_LWEISS_EVENT_PT_D1_18_1_S1-C1_6657.d.zip	Other
	2022_09_20_LWEISS_EVENT_PT_D1_18_2_S1-D1_6658.d.zip	Other
	2022_09_20_LWEISS_EVENT_PT_D1_20_1_S1-E1_6673.d.zip	Other

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Publications

Unique Patterns of Circulating Extracellular Vesicles in Preterm Infants During Adaptation to Extra-Uterine Life.

Murphy Claire A CA O'Reilly Daniel D Weiss Luisa L Madden Stephen S Macleod Hayley H Chevillier Ana Le AL Neary Elaine E O'Loughlin John J El-Khuffash Afif A Kevane Barry B NíAinle Fionnuala F Zivny Jan J McCallion Naomi N Maguire Patricia B PB

Journal of extracellular vesicles 20250401 4

There is growing interest in the role of extracellular vesicles (EVs) in neonatal pathology. This study aimed to characterise circulating EVs following preterm birth. This single-centre prospective observational study included cord and postnatal plasma from preterm (n = 101) and full-term infants (n = 66). EVs were analysed using nanoparticle tracking analysis, flow cytometry, proteomics and procoagulant activity assay. We found changes in the concentration, size, cellular origin and proteomic c ...[more]

PMID: 40194994

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