HDAC3 mediates retinal endothelial cell metabolic reprogramming and angiogenesis
Ontology highlight
ABSTRACT:
INSTRUMENT(S):
ORGANISM(S): Bos Taurus (bovine)
TISSUE(S): Retinal Pigment Epithelium, Epithelial Cell
SUBMITTER: 
Christian Mitchell
LAB HEAD: Abdelrahman Fouda
PROVIDER: PXD065925 | Pride | 2025-10-06
REPOSITORIES: Pride
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| 2024_04_UniProt_Bos_taurus.fasta | Fasta | |||
| FoudaA_091724_01.mzML | Mzml | |||
| FoudaA_091724_01.raw | Raw | |||
| FoudaA_091724_02.mzML | Mzml | |||
| FoudaA_091724_02.raw | Raw |
Items per page: 5 1 - 5 of 44 |
Publications
HDAC3 mediates retinal endothelial cell metabolic reprogramming and angiogenesis.
Mitchell Christian D CD Morris Carol A CA Wild Melissa M Cunningham Ashlynn A Chuesiang Piyanan P Mohammed Aya A AA Nagalo Bolni Marius BM Rusch Nancy J NJ Fouda Abdelrahman Y AY Shosha Esraa E
Acta pharmacologica Sinica 20250929
Pathological retinal neovascularization (NV) contributes to vision loss in diabetic retinopathy (DR) and retinopathy of prematurity, which are the leading causes of blindness in working-age adults and children, respectively. Retinal hypoxia is a key driver of pathological neovascularization that results in uncontrolled vessel sprouting and the formation of immature and leaky blood vessels. Anti-vascular endothelial growth factor and laser therapies are the standard of care to mitigate vision los ...[more]
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