Proteomics

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Human serum proteomics of pancreatic cancer

ABSTRACT: We analyzed a total of 60 human serum samples, including healthy controls, patients with intraductal papillary mucinous neoplasms, and patients with pancreatic ductal adenocarcinoma. Data-dependent acquisition liquid chromatography–tandem mass spectrometry was performed for proteomic profiling.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Blood Serum

DISEASE(S): Pancreatic Cancer

SUBMITTER: Min-Jung Kang  

LAB HEAD: Min-Jung Kang

PROVIDER: PXD067759 | Pride | 2026-06-08

REPOSITORIES: Pride

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20250218_Group_1_01_sample_24_4164.raw Raw
20250218_Group_1_02_sample_24_0520.raw Raw
20250218_Group_1_03_sample_24_0885.raw Raw
20250218_Group_1_04_sample_24_2424.raw Raw
20250218_Group_1_05_sample_24_2475.raw Raw
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Publications

Mass Spectrometry-Driven Proteomic Biomarkers for Serum-Based Detection of Pancreatic Ductal Adenocarcinoma and Intraductal Papillary Mucinous Neoplasm-Associated Invasive Carcinoma.

Jung HyunGyo H   Park Namyoung N   Kim Jaihwan J   Kang Min-Jung MJ  

Cancer medicine 20260501 5

<h4>Background</h4>Pancreatic cancer remains a highly lethal malignancy due to late diagnosis and the lack of effective non-invasive biomarkers for detection, further complicated by biological heterogeneity, including intraductal papillary mucinous neoplasm (IPMN) and IPMN-associated invasive carcinoma (IPMC).<h4>Methods</h4>Serum samples from a discovery cohort (n = 60), including patients with IPMN, IPMC, and pancreatic ductal adenocarcinoma (PDAC), were analyzed using LC-MS/MS-based serum pro  ...[more]

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