Plasma Extracellular Vesicles from PSEN1-E280A and APOE3 Christchurch patients

ABSTRACT: We isolated plasma EVs from MCI PSEN1E280A-APOE3 (n=10, mean age: 46, range 41-54), non-MCI PSEN1E280A-APOE3 (n=10, mean age: 34, range 22-48), and non-MCI PSEN1E280A-APOE3Ch (n=9, mean age: 35, range 16-51) participants, using differential centrifugation. EVs were characterized by nanoparticle tracking analysis, flow cytometry and LC-MS/MS analysis.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Brain, Platelet, Blood Cell, Blood Plasma, Astrocyte, Pericyte Cell

DISEASE(S): Alzheimer's Disease

SUBMITTER: Lina Pineda  

LAB HEAD: Rafael Posada-Duque

PROVIDER: PXD068363 | Pride | 2026-02-02

REPOSITORIES: Pride