Neuropeptidomics of the cockroach Rhyparobia maderae to characterize the neuropeptide landscape of the cockroach's circadian clock

ABSTRACT: The circadian clock of Rhyparobia maderae is the accessory medulla (AME) in the optic lobes of the brain. Controlled by compound ocular photoreceptors, the cockroach clock orchestrates circadian rhythms in physiology and behavior synchronized with environmental light-dark cycles. Approximately 240 neurons, rich in partially co-localized neuropeptides innervate the AME. Since the identity and function of most of these neuropeptides are unknown in the cockroach, we identify the neuropeptidome, a combination of analyses of brain/retrocerebral complex and AME extracts by Q-Exactive Orbitrap mass spectrometry (MS).

INSTRUMENT(S):

ORGANISM(S): Rhyparobia Maderae

TISSUE(S): Brain, Retrocerebral Complex

DISEASE(S): Disease Free

SUBMITTER: Susanne Neupert  

LAB HEAD: Susanne Neupert

PROVIDER: PXD068894 | Pride | 2025-11-17

REPOSITORIES: Pride