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GFP-Tensin 1 phosphoproteomics upon sodium arsenite treatment in U2OS cells

ABSTRACT: Tensin 1 (TNS1) is a key component of integrin adhesion and plays a key role in linking the actin cytoskeleton with the ECM through interaction with integrin heterodimers. TNS1 forms functional and reversible condensates in cells in response to different extracellular stimuli that act as reservoirs of adhesion components. Here we analysed the role of phosphorylation on TNS1 condensation. Using phosphoproteomics of affinity-purified GFP-TNS1 from control and sodium arsenite-treated U2OS cells, we identify the phosphosites regulating TNS1 condensation.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Cell Culture

SUBMITTER: Michal Dibus

LAB HEAD: Johanna Ivaska

PROVIDER: PXD069806 | Pride | 2026-04-24

REPOSITORIES: Pride

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			Action	DRS
	20240822_CTRL_ARS_1-4.sne	Other
	240822_ARS_1.raw	Raw
	240822_ARS_2.raw	Raw
	240822_ARS_3.raw	Raw
	240822_ARS_4.raw	Raw

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