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Immunepeptidome of Coxsackievirus B3 infection models of human enterocyte and antigen presenting cell lines

ABSTRACT: Coxsackieviruses B (CVBs) emerge as candidate environmental triggers for the autoimmunity against pancreatic islet β cells leading to type 1 diabetes. Persistent CVB infections in the gut and pancreas correlate with islet autoantibody seroconversion, suggesting defective antiviral control in predisposed individuals. Recent antiviral and vaccine trials underscore the need to define immune mechanisms at the intestinal entry site. To address this, we investigated how CVB3 modulates antigen presentation in enterocytes and antigen-presenting cells by using immunopeptidomics.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

SUBMITTER: Nicola Ternette

LAB HEAD: Nicola Ternette

PROVIDER: PXD070471 | Pride | 2026-05-07

REPOSITORIES: Pride

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			Action	DRS
	CVB_IVA12.zip	Other
	CVB_W632.zip	Other
	ORLANDO_PRIDESUBMISSION_METADATA_SCP.xlsx	Xlsx
	TC_L243.zip	Other
	checksum.txt	Txt

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