Proteomics

Dataset Information

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Metformin promotes broad neuroprotection and proteostatic resilience via rngo/DDI2 stabilisation


ABSTRACT: Alzheimer’s disease (AD) is one of the most common age-related causes of death, with limited effective disease-modifying treatments. Although metformin shows promise as a disease-modifying agent for AD, its molecular mechanism—specifically how it confers neuroprotection despite potentially increasing amyloid-beta (Ab) load—remains obscure.

INSTRUMENT(S):

ORGANISM(S): Drosophila Melanogaster (fruit Fly)

TISSUE(S): Head

SUBMITTER: riccardo zenezini chiozzi  

LAB HEAD: Konstantinos Thalassinos

PROVIDER: PXD073801 | Pride | 2026-03-03

REPOSITORIES: Pride

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