Detection of KDM1A in cervicovaginal samples from women with high-grade serous ovarian carcinoma: an exploratory pilot study.
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ABSTRACT: Exploratory biomarker studies of high-grade serous ovarian carcinoma (HGSOC) remain challenging in gynaecological oncology due to the lack of reliable, non-invasive diagnostic approaches. Recent evidence suggests that the cervical microenvironment may reflect distal ovarian malignancy through a "field effect," manifesting as epigenetic and proteomic alterations. This study investigates the potential of cervicovaginal sampling (CVS) for HGSOC detection by profiling proteins involved in epigenetic regulation.
INSTRUMENT(S):
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Endocervical Epithelium
DISEASE(S): Malignant Neoplasm Of Ovary
SUBMITTER:
Luc Negroni
LAB HEAD: Frederic DELOM
PROVIDER: PXD076807 | Pride | 2026-04-10
REPOSITORIES: Pride
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