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Systematic mapping of MEK (MEK1, MEK2) interactomes, in WT, inactive, clinically relevant and functional mutations

ABSTRACT: This dataset provides a comprehensive proteomic map of the MEK1 and MEK2 interactomes, utilizing two complementary mass spectrometry (MS) approaches to capture both stable and transient protein-protein interactions (PPIs). A total of 8 functional and clinical mutations of MEK1 was used as bait in addition to the WT. For MEK2, only the WT was used.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Cell Culture

SUBMITTER: Markus Hartl

LAB HEAD: Prof. Dr. Manuela Baccarini

PROVIDER: PXD079313 | Pride | 2026-07-10

REPOSITORIES: Pride

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Dataset's files

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			Action	DRS
	2020.01_UP000005640_9606_Homo_sapiens_canonical.fasta	Fasta
	20200923_QExHFX1_RSLC1_Vucak_Baccarini_MFPL_TurboID_rep1_c1_30p_plusiRT.raw	Raw
	20200923_QExHFX1_RSLC1_Vucak_Baccarini_MFPL_TurboID_rep1_c1plus_30p_plusiRT.raw	Raw
	20200923_QExHFX1_RSLC1_Vucak_Baccarini_MFPL_TurboID_rep1_s10c1_30p_plusiRT.raw	Raw
	20200923_QExHFX1_RSLC1_Vucak_Baccarini_MFPL_TurboID_rep1_s11c1_30p_plusiRT.raw	Raw

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