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Schizosaccharomyces pombe

ABSTRACT: Gene expression profiling analysis of the fission yeast mks1 mutant

PROVIDER: PRJDB15696 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	DRR459935_1.fastq.gz	Fastqsanger.gz
	DRR459935_2.fastq.gz	Fastqsanger.gz
	DRR459936_1.fastq.gz	Fastqsanger.gz
	DRR459936_2.fastq.gz	Fastqsanger.gz
	DRR459937_1.fastq.gz	Fastqsanger.gz

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Heat-shock molecular chaperone Hsp90 is involved in heterochromatin assembly in Schizosaccharomyces pombe.

Project description:Here, we report the high-throughput profiling of histone modification (H3K9me2) in fission yeast Schizosaccharomyces pombe. We generated genome-wide H3K9me2 maps of fission yeast mutants in swo1-26 (temperature sensitive, ts) cells at 25℃ and 37℃. We find that H3K9me2 enrichment at heterochromatin regions, especially at the mating-type locus and subtelomeres, is compromised, suggesting heterochromatin assembly defects.

2020-06-18 | GSE140617 | GEO

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