Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Mus musculus

ABSTRACT: Genome wide mapping of H3.3 in Hindlimb at embryonic day 14.5

PROVIDER: PRJDB2387 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	DRR010319.fastq.gz	Fastqsanger.gz
	DRR010320.fastq.gz	Fastqsanger.gz
	DRR010321.fastq.gz	Fastqsanger.gz
	DRR010322.fastq.gz	Fastqsanger.gz
	DRR010323.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 6

Similar Datasets

Mus musculus

Project description:Genome wide mapping of H3K4me3 in Hindlimb at embryonic day 14.5

| PRJDB2632 | ENA

Mus musculus

Project description:Genome wide mapping of H3K27me3 in Hindlimb at embryonic day 14.5

| PRJDB2659 | ENA

Mus musculus

Project description:Genome wide mapping of H3.3 in Liver at embryonic day 14.5

| PRJDB2061 | ENA

Mus musculus

Project description:Genome wide mapping of H3.3 at embryonic day 10.5

| PRJDB2193 | ENA

Mus musculus

Project description:Genome wide mapping of H3K27me3 in Liver at embryonic day 14.5

| PRJDB1795 | ENA

Mus musculus

Project description:Genome wide mapping of H3K4me3 in Liver at embryonic day 14.5

| PRJDB2348 | ENA

Mus musculus

Project description:Genome wide mapping of H3K4me3 in embryonic day 10.5

| PRJDB1954 | ENA

Mus musculus

Project description:Genome wide mapping of H3K27me3 at embryonic day 10.5

| PRJDB2249 | ENA

Testis expression in Mus musculus domesticus x Mus musculus musculus hybrid zone mice

Project description:We collected whole genome testis expression data from hybrid zone mice. We integrated GWAS mapping of testis expression traits and low testis weight to gain insight into the genetic basis of hybrid male sterility.

2014-12-04 | GSE61417 | GEO

Testis expression in Mus musculus domesticus WSB/EiJ x Mus musculus musculus PWD/PhJ F2 hybrids

Project description:To characterize the genetic basis of hybrid male sterility in detail, we used a systems genetics approach, integrating mapping of gene expression traits with sterility phenotypes and QTL. We measured genome-wide testis expression in 305 male F2s from a cross between wild-derived inbred strains of M. musculus musculus and M. m. domesticus. We identified several thousand cis- and trans-acting QTL contributing to expression variation (eQTL). Many trans eQTL cluster into eleven ‘hotspots,’ seven of which co-localize with QTL for sterility phenotypes identified in the cross. The number and clustering of trans eQTL - but not cis eQTL - were substantially lower when mapping was restricted to a ‘fertile’ subset of mice, providing evidence that trans eQTL hotspots are related to sterility. Functional annotation of transcripts with eQTL provides insights into the biological processes disrupted by sterility loci and guides prioritization of candidate genes. Using a conditional mapping approach, we identified eQTL dependent on interactions between loci, revealing a complex system of epistasis. Our results illuminate established patterns, including the role of the X chromosome in hybrid sterility.

2014-05-01 | GSE54089 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data