Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Homo sapiens

ABSTRACT: liver miRNA expression profiles of HCC/CCC patients

PROVIDER: PRJDB2866 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	DRR018591.fastq.gz	Fastqsanger.gz
	DRR018592.fastq.gz	Fastqsanger.gz
	DRR018593.fastq.gz	Fastqsanger.gz
	DRR018594.fastq.gz	Fastqsanger.gz
	DRR018595.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 48

Similar Datasets

Homo sapiens

Project description:mRNA/microRNA expression profiles of HCC or CCC patients' liver, together with those of non-tumor part tissues

| PRJNA246722 | ENA

mRNA/microRNA expression profiles of HCC or CCC patients' liver, together with those of non-tumor part tissues

Project description:11 CCC and 5 HCC patients' tumor and non-tumor parts tissues are extracted. Then total RNA are purified from tissues and mRNA and miRNA profiles are measured using agilent one color microarrays designed for mRNA or microRNA expression profiles.

2015-12-21 | GSE57555 | GEO

mRNA/microRNA expression profiles of HCC or CCC patients' liver, together with those of non-tumor part tissues

2015-12-21 | E-GEOD-57555 | biostudies-arrayexpress

Homo sapiens

Project description:Differential miRNA expression profiles betweenHBV-related HCC tumor versus non-tumor liver tissue

| PRJNA285950 | ENA

Homo sapiens foetal mesenchymal stem cell miRNA transcriptome

Project description:We have sequenced miRNA libraries from human embryonic, neural and foetal mesenchymal stem cells. We report that the majority of miRNA genes encode mature isomers that vary in size by one or more bases at the 3’ and/or 5’ end of the miRNA. Northern blotting for individual miRNAs showed that the proportions of isomiRs expressed by a single miRNA gene often differ between cell and tissue types. IsomiRs were readily co-immunoprecipitated with Argonaute proteins in vivo and were active in luciferase assays, indicating that they are functional. Bioinformatics analysis predicts substantial differences in targeting between miRNAs with minor 5’ differences and in support of this we report that a 5’ isomiR-9-1 gained the ability to inhibit the expression of DNMT3B and NCAM2 but lost the ability to inhibit CDH1 in vitro. This result was confirmed by the use of isomiR-specific sponges. Our analysis of the miRGator database indicates that a small percentage of human miRNA genes express isomiRs as the dominant transcript in certain cell types and analysis of miRBase shows that 5’ isomiRs have replaced canonical miRNAs many times during evolution. This strongly indicates that isomiRs are of functional importance and have contributed to the evolution of miRNA genes

2014-08-06 | GSE58734 | GEO

Micro RNA expression from human hepatocellular carcinoma (HCC) specimens from patients undergoing liver transplantation.

Project description:Current selection criteria for liver transplant in patients with HCC (the Milan criteria) do not incorporate biologic metrics. MiRNA expression profiles correlate with HCC recurrence after transplant and can add significant value to the Milan criteria. MiRNA expression profiles were studied in HCC specimens from patients undergoing liver transplant and correlated with their tumor recurrence status and Milan criteria status.

2011-10-14 | E-GEOD-30297 | biostudies-arrayexpress

Micro RNA expression from human hepatocellular carcinoma (HCC) specimens from patients undergoing liver transplantation.

2011-10-15 | GSE30297 | GEO

Homo sapiens

Project description:miRNA profiles of HCC from Southeast China

| PRJNA112655 | ENA

Plasma miRNA profiling in patients with hepetocellular carcinoma and liver cirrhosis

Project description:To evaluate the potential of circulating microRNAs as biomarkers for early hepetocellular carcinoma (HCC) screening, plasma miRNA profiles were compared between patients with HCC and liver cirrhosis (LC).

2025-06-12 | GSE294055 | GEO

Homo sapiens

Project description:Gene expression in liver of HCC and CHC patients

| PRJNA192880 | ENA